|
KMID : 1007420120100010037
|
|
Mood and Emotion
2012 Volume.10 No. 1 p.37 ~ p.42
|
|
|
The Patterns of Antidepressant Prescription and Associated Factors in Psychiatric Inpatient at a University Hospital
|
|
Ryu Kwon-Ho
Park Sang-Hag
Kim Hack-Ryul
Kim Sang-Hoon
Shin Hye-Rang
|
|
|
Abstract
|
|
|
Objectives : The goal of this study was to examine the trend of antidepressant prescription patterns and associating factors at a university hospital.
Methods : Subjects were total 138 psychiatric inpatients who take antidepressants for two years, 2008 and 2009 at a university hospital. We evaluated antidepressants used as the first choice, switching, combination , various augmentation agents and the factor associated with choice of antidepressant.
Results : The antidepressants used as first line drug were Selective Serotonin Reuptake Inhibitor (SSRI)(51.4%), Noradrenergic and Specific Serotonergic Antidepressant (NaSSA)(21.7%), Serotonin Noradrenaline Reuptakte Inhibitor (SNRI)(13.8%) in frequency order. The antidepressants used as switching drug were SNRI (35.7%), NaSSA (28.6%), and SSRI (21.4%). As combination treatment, various combination were used including NaSSA, Tricyclic Antidepressants (TCA), SNRI (29.4%, 29.4%, 20.6%, respectively). As augmentation treatment, atypical antipsychotics (44.2%) more used frequently than trazodone (38.4%), mood stabilizer (16.3%). The factor associated with choice of antidepressant were not different significantly.
Conclusion : Psychiatrists in a university hospital prefer combination medication to switching antidepressant. These changes could be seen in use of various antidepressants, increment in use of atypical antipsychotics. The result of the present study that there was no significant factor associated with choice of antidepressant. This study can reflect not only the current progress of psychopharmacology and clinical experience, but also the clinical complexity of prescription of antidepressant.
|
|
|
KEYWORD
|
|
|
Antidepressant, Prescription pattern, Associated factor
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
 
|
|